James Ding
May 16, 2025 03:52
UCSD researchers use AI to identify genes PHGDH as a cause of Alzheimer’s, leading to potential new treatment options.
Artificial intelligence is innovating the understanding of Alzheimer’s disease as the researchers at the University of California of San Diego (UCSD) play a gene that plays a direct role in causing the state. According to NVIDIA, the previously considered gene PHGDH is now confirmed as a cause factor and provides a new way for treatment.
The groundbreaking result of Alzheimer’s research
The UCSD study published in the Cell Journal shows that PHGDH interferes with the normal gene control of the brain and causes voluntary Alzheimers. Genetic mutations are the central tribe because it explains only a small part of the Alzheimer’s case among more than 7 million Americans affected by the disease. Identify the cause of non -spirituality is important for treatment.
The role of AI to identify major genetic functions
Using the advanced AI model, the researchers have confirmed the harmful secondary function of PHGDH. The study explored the role of PHGDH in the disease progression using the NVIDIA RTX A6000 and H100 GPUs for the computational intensive model, including potential prompt transformers.
Potential treatment through AI -centered discovery
In addition to identifying the role of genes, the AI model pointed out NCT-503, a promising treatment candidate. The test in the mouse showed significant slowdown in the progression of the disease and the improvement of cognition, showing the potential innovation of treatment.
Future direction and clinical impact
Sheng Zhong, the senior author and professor of UCSD, emphasized the potential to develop a completely new type of small molecule for the treatment of Alzheimer’s. The team plans to optimize the compound and conduct additional preclinical research before being approved by the FDA.
This breakthrough study emphasizes the modified effects of AI in solving the variant of AI on medicine, especially complex biological interactions and developing new treatments.
Image Source: Shutter Stock